Journal of Clinical Epidemiology

The scoping review highlights the crucial need for standardized reporting of health equity in research studies.
During their investigation, the researchers identified 13 additional items that can significantly contribute to the understanding and reporting of health equity. These items cover various aspects, such as defining health equity terms, acknowledging the role of racism and discrimination, considering the composition and training of researchers, incorporating relevant factors in study methods, and facilitating data sharing across equity factors. This comprehensive approach aims to provide a holistic perspective on health equity.

A scoping review establishes need for consensus guidance on reporting health equity in observational studies To evaluate the support from the available guidance on reporting of health equity in research for our candidate items and to identify additional items for the STROBE (Strengthening Reporting of Observational studies in Epidemiology)-Equity extension.

Authors often rely on statistical significance alone and may overlook meaningful differences in nonsignificant effect estimates

Beyond Statistical Significance: Nuanced Interpretations of Statistically Nonsignificant Results were Rare in Cochrane Reviews – a Meta-epidemiological Study To assess the language used by systematic review authors to emphasize that statistically nonsignificant results show meaningful differences. To determine whether the magnitude of these treatment effects was distinct from nonsignificant results that authors interpreted as not different.

https://www.jclinepi.com/article/S0895-4356%2823%2900089-6/fulltext

The BIGG-REC database makes available all WHO/PAHO evidence-informed recommendations

The BIGG-REC database makes available all WHO/PAHO evidence informed recommendations To build and maintain a living database of the Pan American Health Organization/World Health Organization (PAHO/WHO) recommendations developed using GRADE.

The Journal of Clinical Epidemiology is publishing a special issue on Methodological Considerations Related to Equity, Diversion, and Inclusion (EDI) in Clinical Epidemiology. Articles in this special issue will discuss specific methods challenges and solutions related to EDI. All submissions must have a methodological focus. We welcome submissions addressing both quantitative and/or qualitative methods.

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https://www.jclinepi.com/article/S0895-4356(22)00085-3/fulltext

The GIN-McMaster guideline tool extension for the integration of quality improvement and quality assurance in guidelines: a description of the methods for its development Our objective was to develop an extension of the widely used GIN-McMaster Guideline Development Checklist and Tool for the integration of quality assurance and improvement (QAI) schemes with guideline development.

https://www.jclinepi.com/article/S0895-4356(22)00304-3/fulltext

Assessing the certainty of evidence of test accuracy studies when there are challenges with establishing a reference standard The commentary published by Dr Reed (ref) highlights challenges that decision-makers, including guideline developers, face when approaching evidence about diagnostic imaging tests. Specifically, the important challenges relate to when the reference standard for a test: 1. is not clearly defined or e...

https://www.jclinepi.com/article/S0895-4356(22)00344-4/fulltext

Methods for Living Guidelines: Early Guidance based on practical experience. Paper 1: Introduction To introduce methods for living guidelines based in practical experiences by the Australian Living Evidence Consortium (ALEC), the National Institute of Health and Care Excellence (NICE) and the Infectious Diseases Society of America (IDSA), with methodological support from the United States (US) Gr...

https://www.jclinepi.com/article/S0895-4356(23)00026-4/fulltext

The life and death of living systematic reviews: a methodological survey The objectives of this study are to describe the characteristics of Living Systematic Reviews (LSRs) and to understand their life cycles.

https://www.jclinepi.com/article/S0895-4356(23)00028-8/fulltext

A Delphi consensus checklist helped assess the need to develop rapid guideline recommendations We aimed to develop a checklist to aid guideline developers in determining which scientific or societal cause (‘triggers’) are relevant when considering to initiate a rapid recommendation procedure.

https://www.jclinepi.com/article/S0895-4356(23)00032-X/fulltext

CEAs sponsored by the industry were more likely to report ICERs below $50,000/QALY (adjusted odds ratio (OR), 1.91, 95% confidence interval (CI), 1.45-2.51, p

Sponsorship bias in oncology cost effectiveness analysis Cost effectiveness analysis (CEA) has been increasingly used to inform cancer treatment coverage policy making worldwide. The primary objective of this study was to assess the association between industry sponsorship and CEA results in oncology.