07/06/2026
Moving Mindfulness - Meditation & Fitness
One to one and online Pilates & Personal Training, Meditation and philosophical musings in Aylesbury Personal trainer and nutrition in Aylesbury and the UK.
This is for anyone dedicated to improving their fitness and health through exercise and good nutrition.
07/06/2026
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๐๐ฒ๐ฎ๐๐ ๐๐. ๐๐ถ๐ด๐ต๐ ๐ช๐ฒ๐ถ๐ด๐ต๐๐: ๐ฌ๐ผ๐๐ฟ ๐๐ถ๐ผ๐น๐ผ๐ด๐ ๐๐ถ๐ฐ๐๐ฎ๐๐ฒ๐ ๐ ๐๐๐ฐ๐น๐ฒ ๐๐ฟ๐ผ๐๐๐ต ๐ ๐ผ๐ฟ๐ฒ ๐ง๐ต๐ฎ๐ป ๐๐ต๐ฒ ๐๐ผ๐ฎ๐ฑ ๐ฌ๐ผ๐ ๐๐ถ๐ณ๐
โฌ A fascinating study published in The Journal of Physiology by Lees et al. set out to settle a persistent debate in fitness and muscle physiology: does lifting heavy weights build more muscle than lifting lighter weights, and why do some people grow so much more muscle than others on the same program.
โฌ The researchers wanted to determine whether the massive interindividual variability (the differences from person to person) in muscle growth is driven by exogenous factors like how heavy the weight is or endogenous factors an individual's inherent biological response.
๐งช ๐ง๐ต๐ฒ ๐ฆ๐๐๐ฑ๐ ๐๐ฒ๐๐ถ๐ด๐ป: ๐ ๐๐น๐ฒ๐๐ฒ๐ฟ "๐ช๐ถ๐๐ต๐ถ๐ป-๐ฆ๐๐ฏ๐ท๐ฒ๐ฐ๐" ๐๐ฝ๐ฝ๐ฟ๐ผ๐ฎ๐ฐ๐ต
โฌ To isolate the variable of genetics, the researchers used a clever unilateral (one-sided) study design.
โฌ They recruited 20 healthy, untrained young males for a 10-week resistance exercise training program.
โฌ Participants trained three times per week, performing knee extensions for the legs and dumbbell preacher curls for the arms.
โฌ Here is how their limbs were assigned:
๐ช Higher Load (HL)
โฌ One arm and one leg were assigned to lift heavier weights for 8โ12 repetitions at ~70%โ80% of their 1-repetition maximum.
๐๏ธ Lower Load (LL)
โฌ The opposite arm and opposite leg lifted lighter weights for 20โ25 repetitions at ~30%โ40% of their 1-repetition maximum.
โ ๏ธ The Crucial Detail
โฌ For every single set, the participants lifted until they reached volitional fatigueโthe point where they could not complete another rep with proper form.
๐ ๐ช๐ต๐ฎ๐ ๐ง๐ต๐ฒ๐ ๐ ๐ฒ๐ฎ๐๐๐ฟ๐ฒ๐ฑ
โฌ The researchers used a highly comprehensive suite of testing methods to measure changes over the 10 weeks.
๐ Muscle Size
โฌ Dual-energy X-ray absorptiometry for lean mass, ultrasonography for muscle thickness and cross-sectional area, and muscle biopsies to measure individual muscle fibre size.
๐ช Muscle Strength
โฌ Measured via 1-repetition maximum tests and maximum voluntary isometric contractions.
๐งฌ Protein Synthesis
โฌ Using deuterated water (heavy water) to trace and measure integrated myofibrillar protein synthesis rates at Week 1 and Week 10.
๐ฌ ๐ง๐ต๐ฒ ๐๐ฒ๐ ๐๐ถ๐ป๐ฑ๐ถ๐ป๐ด๐
1๏ธโฃ ๐๐ผ๐ฎ๐ฑ ๐๐ผ๐ฒ๐ ๐ก๐ผ๐ ๐๐ฒ๐๐ฒ๐ฟ๐บ๐ถ๐ป๐ฒ ๐ ๐๐๐ฐ๐น๐ฒ ๐ฆ๐ถ๐๐ฒ
โฌ Whether the limbs lifted heavy weights for 8-12 reps or light weights for 20-25 reps, the muscle hypertrophy was remarkably similar.
โฌ There were no significant differences between the higher load and lower load conditions for any outcome measuring muscle size including lean mass, whole-muscle thickness, or microscopic fibre size.
๐งฌ 2๏ธโฃ ๐ฌ๐ผ๐๐ฟ ๐๐ป๐ต๐ฒ๐ฟ๐ฒ๐ป๐ ๐๐ถ๐ผ๐น๐ผ๐ด๐ ๐๐ถ๐ฐ๐๐ฎ๐๐ฒ๐ ๐ฌ๐ผ๐๐ฟ ๐๐ฟ๐ผ๐๐๐ต
โฌ The study found that a person's muscle growth was highly "conserved" within their own body.
โฌ This means if a participant's right arm grew a lot from heavy lifting, their left arm also grew a lot from light lifting, and their legs likely saw high growth too.
โฌ The variability between different people was massive, but the variability within the same person's different limbs and loading protocols was very low.
โฌ The researchers concluded that endogenous biological factors are the primary drivers of muscle growth, accounting for a vast majority of the differences we see between individuals.
โ๏ธ 3๏ธโฃ ๐ ๐๐๐ฐ๐น๐ฒ ๐ฃ๐ฟ๐ผ๐๐ฒ๐ถ๐ป ๐ฆ๐๐ป๐๐ต๐ฒ๐๐ถ๐ ๐ฆ๐ฝ๐ถ๐ธ๐ฒ๐ ๐๐ฎ๐ฟ๐น๐, ๐ง๐ต๐ฒ๐ป ๐๐ฎ๐ฑ๐ฒ๐
โฌ Myofibrillar protein synthesis the biological process of building new muscle tissue spiked significantly during the first week of training compared to baseline resting levels.
โฌ Interestingly, by week 10, this protein synthesis rate was significantly blunted despite the participants utilizing progressive overload.
โฌ Furthermore, just like the actual size gains, protein synthesis rates were comparable between the heavy and light load conditions.
๐๏ธ 4๏ธโฃ ๐ฆ๐ถ๐๐ฒ ๐ฎ๐ป๐ฑ ๐ฆ๐๐ฟ๐ฒ๐ป๐ด๐๐ต ๐๐ฟ๐ฒ ๐ก๐ผ๐ ๐ฆ๐๐ฟ๐ผ๐ป๐ด๐น๐ ๐๐ถ๐ป๐ธ๐ฒ๐ฑ
โฌ While both heavy and light loads increased 1-repetition maximum strength and isometric peak torque.
โฌ The researchers noted negligible shared variance between a participant's muscle size increases and their strength increases.
โฌ Simply put, the participants who gained the most muscle size were not necessarily the ones who gained the most strength.
โ
๐ง๐ต๐ฒ ๐๐ถ๐ด ๐ง๐ฎ๐ธ๐ฒ๐ฎ๐๐ฎ๐
โฌ When effort is matched by pushing sets to volitional fatigue, lifting heavy weights and lifting light weights will build the exact same amount of muscle.
โฌ You don't have to lift heavy to get bigger.
โฌ Ultimately, how much muscle you build is dictated to a far greater degree by your intrinsic biology rather than the specific loading scheme of your program. ๐ช
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